Hyperbaric Oxygen Therapy
COVID-19 and Hyperbaric Oxygen Therapy
The SARS-CoV-2 virus which causes COVID-19 primarily attacks the respiratory system. Front line doctors report patients with rapidly declining oxygen saturation needing mechanical ventilation to reverse low oxygen saturation (medically known as hypoxia). Patients are not dying from lung failure but from oxygen failure, namely prolonged oxygen deprivation.
The current approach to treating COVID-19 is similar to that of viral pneumonia [1], with the severely ill requiring the assistance of mechanical ventilation. While countries are stocking up on ventilators, new evidence is arising from New York City's emergency doctors' experience suggesting they may not be effective enough [1,2]; it is not lung failure which causes death among COVID-19 patients, but systemic and prolonged oxygen deprivation (hypoxia).
Oxygen deprivation is similar to altitude sickness among mountaineers who are exposed to "thin air" (lower partial pressure of oxygen available to breathe) and to carbon monoxide poisoning (carbon monoxide molecules occupying the oxygen sites on the hemoglobin, preventing oxygenation). In all these cases, the oxygen deficit can be balanced by exposing the whole body to an increased concentration of oxygen, such as during hyperbaric oxygen therapy (HBOT).
Hyperbaric oxygen therapy and COVID-19
Like any virus, COVID-19 propagates more effectively in a hypoxic and immunocompromized body. Hyperbaric oxygen therapy creates super-oxygenation (hyperoxia). It is used in strengthening the immune system to give it a better chance at fighting off infections.
Hypoxic conditions can be reversed with hyperoxia, - super-oxygenation. This is done by breathing pure oxygen under pressure inside hyperbaric chambers.
HBOT is the administration of 100% medical oxygen under pressure and is specifically designed to address hypoxia. At one atmosphere (sea level atmospheric pressure), the healthy haemoglobin will be 100% saturated with oxygen during HBOT. Additional oxygen can be delivered at elevated pressures. At three atmospheres during HBOT, up to 20 times more oxygen is dissolved in the bodily fluids, including the blood plasma, lymphatic, and cerebrospinal fluids.
Providing safety to our staff and our clients is imperative to us at BaroMedical. Our safety and infection control protocols are following hyperbaric medicine, our government and WHO recommendations. We can offer and individualized and customized therapy in single occupancy, oxygen compressed, see thru chambers built to the highest standard minimizing cross contamination during hyperbaric oxygen therapy.
Although HBOT cannot eradicate the virus causing COVID-19, it will provide oxygen to the hypoxic tissue, as well as support the body's immune system. The therapy may delay or reduce severe complications, potentially avoiding the need for mechanical ventilation altogether.
RESEARCH NEWS:
A recent study from Israel shows that 40 hyperbaric oxygen sessions can significantly improve neurocognitive functions and symptoms in patients suffering from post-COVID-19 condition.
This randomized, sham control, double blind clinical trial was conducted by the Shai Efrati and Amir Haddany's research group at the Sagol Center for Hyperbaric Medicine and Research and School of Neuroscience, at the Tel-Aviv University in Tel‑Aviv, Israel. This is the latest addition to a leading research of the Israeli scientists supporting evidence that hyperbaric oxygenation or HBOT improves the brain plasticity in people with fibromyalgia , traumatic brain injury TBI and stroke as well as in healthy senior individuals.
Results of the study showed improvement in global cognitive function, attention and executive power, elevated energy levels, better sleep, reduced anxiety and depression, and overall systemic pain. These clinical improvements were associated with significant improvement in oxygenation leading to increased perfusion of the brain and microstructural changes confirmed with MRI of the brain. The authors conclude that "HBOT’s beneficial effect may be attributed to increased brain perfusion and neuroplasticity in regions associated with cognitive and emotional roles."
Post Covid-19 or long Covid condition is defined as a myriad of symptoms including psychological, physical, emotional that are continuing or even new developing more than three months after getting Covid-19. Usual symptoms are trouble breathing and cough, heart problems with chest pain and palpitations, digestive problems with diarrhea and stomach pain, trouble thinking and concentrating ("brain fog"), headaches, anxiety, depression, reduced executive function, sleep problems and systemic widespread pain. The induced damage of infection with Covid-19 reaches cellular levels with hypoxia, inflammation and ischemia. This last study confirms the neuroplasticity effects of HBOT, including anti-inflammatory, mitochondrial function restoration, increased perfusion via angiogenesis and induction of proliferation and migration of stem cells.
The benefits of hyperbaric oxygenation in post Covid -19 infection and infections in general are in its role as powerful and non invasive systemic therapy that is also an excellent adjunctive therapy to other medical and natural treatments and therapies.
Read more on Long COVID recovery with hyperbaric oxygen therapy
and Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID
Further reading:
- Shani Zilberman‑Itskovich, et al., Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post‑COVID condition: randomized controlled trial; Scientifc Reports | (2022) 12:11252 | https://doi.org/10.1038/s41598-022-15565-0
- Mahrumi Dewi Tri Utami, et al., Hyperbaric oxygen therapy as a potential therapy for new-onset diabetes mellitus in post-COVID-19 syndrome: current evidence; IJRP 2022, 92(1), 53-63; doi:.10.47119/IJRP100921120222654
- M Catalogna, et al., Effects of hyperbaric oxygen therapy on functional and structural connectivity in post-COVID-19 condition patients: A randomized, sham-controlled trial; NeuroImage: Clinical 36 (2022) 103218
- Areeg A Abu El Hawa, et al., The evolving use of hyperbaric oxygen therapy during the COVID-19 pandemic; J Wound Care N American Supp Vol 30(2) Feb 2021
- S Alinaghi, et al., Predictors of the prolonged recovery period in COVID-19 patients: a cross-sectional study; Eur J Med Res (2021) 26:41
- C del Rio, et al., Long-term Health Consequences of COVID-19; JAMA November 3, 2020 Volume 324, Number 17
- A M Bhaiyat, et al., Hyperbaric oxygen treatment for long coronavirus disease-19: a case report; Bhaiyat et al. Journal of Medical Case Reports (2022) 16:80
- Robbins, et al., Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention; Clinical Medicine 2021 Vol 21, No 6: e629–32
- Ghose M, Islam T, Facing the Challenge of Post COVID-19 Pulmonary fibrosis: What is so unique about it?; Bangladesh Crit Care J September 2020; 8 (2): 102-107
- Kyle-Sidell C. Doctor From NY City Offers His Observations on COVID-19. Armstrong Economics. Published April 13, 2020
- Whyte J, Kyle-Sidell C. Do COVID-19 Ventilation Protocols Need a Second Look? Medscape. Published April 6, 2020
- NYU Langone Health.Clinical Trial: Hyperbaric Oxygen for COVID-19 Patients. Clinical Trials. Published April 2020.
- Undersea & Hyperbaric Medical Society.UHMS Guidelines for Infection Control, Patient Treatment, and Staff Safety Considerations Related to Hyperbaric Oxygen Therapy (HBO2) in Monoplace and Multiplace Hyperbaric Chambers during the Novel Coronavirus Disease (COVID-19) Outbreak.; 2020.
- European Committee for Hyperbaric Medicine.ECHM Position on Hyperbaric Oxygen Therapy (HBOT) in Multiplace Hyperbaric Chambers during Coronavirus Disease (COVID-19) Outbreak.; 2020.
- Centers for Disease Control and Prevention.Infection Control: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) .
- World Health Organization.World Health Organization: Q&A on COVID-19.
- Government of Canada.Coronavirus disease (COVID-19): Prevention and risks . Government of Canada.
- Dr. Katz, Medical Director Hyperbaric Medical Solutions HMS Medical Director Discusses HBOT As Possible Solution For COVID-19 On CBS News Radio Show 'KNX In Depth'
- Experimental Coronavirus Treatment That Removes Blood, Pumps It Full Of Oxygen And Returns It To The Body 'Saves' Two US Patients Who Were On Ventilators
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